bs-1583R [Primary Antibody]
SP-D/PSPD Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SP-D/PSPD

Immunogen Range: 301-375/375


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6441

Swiss Prot: P35247

Source: KLH conjugated synthetic peptide derived from human SP-D

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 41


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Sung, Hsin-Ching, et al. "The protective effect of eupafolin against TNF-α-induced lung inflammation via the reduction of intercellular cell adhesion molecule-1expression." Journal of Ethnopharmacology (2015).Read more>>
  • Ferretti, Andrew, et al. "Autoantibody-Mediated Pulmonary Alveolar Proteinosis in Rasgrp1-Deficient Mice." The Journal of Immunology (2016): 1502248.Read more>>
  • Furukawa et al. Databases for technical aspects of immunohistochemistry. (2017) J.Toxicol.Patho. 30:79-107Read more>>
  • Chen et al. Functional roles of C/EBPα and SUMO‑modification in lung development. (2017) Int.J.Mol.Me. 40:1037-1046Read more>>
  • Malvin NP et al. Autophagy proteins are required for club cell structure and function in airways. Am J Physiol Lung Cell Mol Physiol. 2019 May 22.Read more>>
  • Meng Guoet al. Inhibition of miR-93 promotes interferon effector signaling to suppress influenza A infection by upregulating JAK1. Int Immunopharmacol. 2020 Sep;86:106754.Read more>>
  • Shota Mitsuboshi. et al. A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy. Regen Ther. 2022 Mar;19:113Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-SP-D/PSPD Polyclonal Antibody, Unconjugated(bs-1538R) at 1:200, followed by conjugation to the secondary antibody and DAB staining.


Formalin-fixed and paraffin embedded mouse lung tissue labeled Anti-SP-D Polyclonal Antibody, Unconjugated (bs-1583R) at 1:2000, followed by conjugation to the secondary antibody and DAB staining