bs-1559R-Cy5 [Conjugated Primary Antibody]
GLP-1R Polyclonal Antibody, Cy5 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: GLP-1R

Immunogen Range: 101-200/463


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 25051

Swiss Prot: P32301

Source: KLH conjugated synthetic peptide derived from rat GLP-1R

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 51


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhou, Hao, et al. "Exendin-4 protects ADMSCs from apoptosis induced by Hydrogen peroxide through PI3K/Akt-Sfrp2 pathways." Free Radical Biology and Medicine (2014).Read more>>
  • Nagai, Takuo, et al. "Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in Mice." PLOS ONE 11.8 (2016): e0160993.Read more>>
  • Kanda et al. Expression of the glucagon-like peptide-1 receptor and its role in regulating autophagy in endometrial cancer. (2018) BMC.Cancer. 18:657Read more>>
  • "Wen Y et al. Inhibitory effects of glucagon-like peptide-1 receptor on epilepsy. Biochem Biophys Res Commun. 2019 Mar 26;511(1):79-86."Read more>>
  • Kim SJ et al. DPP-4 inhibition enhanced renal tubular and myocardial GLP-1 receptor expression decreased in CKD with myocardial infarction.BMC Nephrol. 2019 Mar 1;20(1):75. Read more>>
  • Shan Y et al. The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke. J Neuroinflammation. 2019 Nov 28;16(1):242.Read more>>
  • Melek T et al. Ileal interposition improves metabolic syndrome parameters in a rat model of metabolic syndrome induced by monosodium glutamateLife Sci.2020 Dec 9;266:118846.Read more>>
  • Shuangli Yang. et al. Glucagon-like peptide-1 alleviates diabetic kidney disease through activation of autophagy by regulating AMP-activated protein kinase-mammalian target of rapamycin pathway. Am J Physiol-Endoc M. 2020 Nov;319(6):E1019-E103Read more>>
  • Liu Jinlei. et al. Emodin Attenuated the Kidney Damage of High-Fat-Diet Mice via the Upregulation of Glucagon-Like Peptide-1 Receptor. Biomed Res Int. 2021;2021:6662704Read more>>
  • Haoqiang Zhang. et al. Glucagon-like peptide-1 attenuated carboxymethyl lysine induced neuronal apoptosis via peroxisome proliferation activated receptor-. Aging-Us. 2021 Jul 31; 13(14): 19013C19027Read more>>
  • Yuping Chen. et al. The Herb Pair Radix Rehmanniae and Cornus Officinalis Attenuated Testicular Damage in Mice With Diabetes Mellitus Through Butyric Acid/Glucagon-Like Peptide-1/Glucagon-Like Peptide-1 Receptor Pathway Mediated by Gut Microbiota. Front Microbiol. 2022 Feb 22;13:831881Read more>>
  • Zhan-zhao Liu. et al. Glucagon-like peptide-1 receptor activation by liraglutide promotes breast cancer through NOX4/ROS/VEGF pathway. Life Sci. 2022 Apr;294:12037Read more>>
  • Hongzeng Li. et al. Eugenol alleviated nonalcoholic fatty liver disease in rat via a gut-brain-liver axis involving glucagon-like Peptide-1. ARCH BIOCHEM BIOPHYS. 2022 May;:109269Read more>>
  • Wu Li. et al. GLP1R inhibits the progression of endometrial carcinoma through activation of cAMP/PKA pathway. J CLIN LAB ANAL. 2022 Aug;:e24604Read more>>
  • Qiaoji Tian. et al. Glucagon-Like Peptide-1 Receptor Mediates the Improvement in Glycolipid Metabolism Disorder via AKT and AMPK Signalling Pathways in L02 Cells with Insulin Resistance. J MOL STRUCT. 2022 Oct;:134328Read more>>
  • Li Xu. et al. Oleanolic acid and moderate drinking increase the pancreatic GLP-1R expression of the -cell mass deficiency induced hyperglycemia. PEERJ. 2023 Jul;11:e15705Read more>>
  • Qi Ruibing. et al. Liraglutide improved the reproductive function of obese mice by upregulating the testicular AC3/cAMP/PKA pathway. REPROD BIOL ENDOCRIN. 2024 Dec;22(1):1-1Read more>>
  • Pengfei Lv. et al. Intestinal Perfusion of Unacylated Ghrelin Alleviated Metabolic Associated Fatty Liver Disease in Rat via a Central Glucagon-Like Peptide-1 Pathway. AM J PHYSIOL-GASTR L. 2024 Apr;(Articles in Press)Read more>>
  • Shaobin Yang. et al. Neuronostatin regulates neuronal function and energetic metabolism in Alzheimer's disease in a GPR107-dependent manner. NEUROPHARMACOLOGY. 2024 Nov;258:11009Read more>>
  • Shaobin Yang. et al. Tirzepatide shows neuroprotective effects via regulating brain glucose metabolism in APP/PS1 mice. PEPTIDES. 2024 Jul;:171271Read more>>
VALIDATION IMAGES