bs-1545R-Biotin [Conjugated Primary Antibody]
TPA Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: TPA

Immunogen Range: 485-562/562


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5327

Swiss Prot: P00750

Source: KLH conjugated synthetic peptide derived from human Tissue-type plasminogen activator chain B

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 28/58


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Balaoing, Liezl R., et al. "Age-Related Changes in Aortic Valve Hemostatic Protein Regulation." Arteriosclerosis, Thrombosis, and Vascular Biology (2013): ATVBAHA-113.Read more>>
  • Makuszewska, Maria. et al. Enhanced Expression of Plasminogen Activators and Inhibitor in the Healing of Tympanic Membrane Perforation in Rats. JARO-J ASSOC RES OTO. 2023 Feb;:1-12Read more>>
VALIDATION IMAGES