DATASHEET
Host:
Rabbit
Target Protein:
C9orf173
Immunogen Range:
201-300/389
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
441476
Source:
KLH conjugated synthetic peptide derived from human C9orf173
Purification:
Purified by Protein A.
Storage Buffer:
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
C9orf173 (chromosome 9 open reading frame 173) is a 389 amino acid protein that exists as four alternatively spliced isoforms. The gene encoding C9orf173 maps to human chromosome 9q34.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Conjugation:
Cy3
Excitation/ Emission:
512,550nm/570,615nm
Size:
100ul
Concentration:
1ug/ul
Applications:
WB(1:300-5000)
43
Mouse
Predicted Cross Reactive Species:
Human
Rat
Dog
For research use only. Not intended for diagnostic or therapeutic use.