bs-1502R-Cy3 [Conjugated Primary Antibody]
CXCL10 Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CXCL10

Immunogen Range: 35-98/98


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 15945

Swiss Prot: P17515

Source: KLH conjugated synthetic peptide derived from mouse CXCL10

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 10


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Li, Yu-Tung, Tomoyuki Nishikawa, and Yasufumi Kaneda. "Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation." Scientific Reports 6 (2016): 25077.Read more>>
  • Djamiatun, Kis, et al. "Annona muricata modulate brain-CXCL10 expression during cerebral malaria phase." IOP Conference Series: Earth and Environmental Science. Vol. 55. No. 1. IOP Publishing, 2017.Read more>>
  • Iversen, Marie B., et al. "An innate antiviral pathway acting before interferons at epithelial surfaces." Nature immunology (2015).Read more>>
  • Clancy-Thompson, Eleanor, et al. "Melanoma induces, and adenosine suppresses, CXCR3-cognate chemokine production and T-cell infiltration of lungs bearing metastatic-like disease." Cancer immunology research 3.8 (2015): 956-967.Read more>>
  • Henschel et al. Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility. (2018) PLoS.One. 13:e0190351Read more>>
  • Lee et al. Establishment of a chronic obstructive pulmonary disease mouse model based on the elapsed time after LPS intranasal instillation. (2018) Lab.Anim.Res. 34:01-OctRead more>>
  • Günther et al. Defective removal of ribonucleotides from DNA promotes systemic autoimmunity. (2015) J.Clin.Invest. 125:413-24Read more>>
  • Kang et al. Tissue-Specific Regulation of p38α-Mediated Inflammation in Con A-Induced Acute Liver Damage. (2015) J.Immunol. 194:4759-66Read more>>
  • Yang R et al. Cordycepin Attenuates IFN-γ-Induced Macrophage IP-10 and Mig Expressions by Inhibiting STAT1 Activity in CFA-Induced Inflammation Mice Model. Inflammation. 2019 Dec 23.Read more>>
  • Manuel Z et al. Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the bloodCbrain barrierSci Rep.2020 Dec 24;10(1):22383.Read more>>
  • Hu Sun. et al. Study on the relationship between CXCR3 and its ligands and tubal tuberculosis. Life Sci. 2021 May;272:119047Read more>>
  • Xin Hu. et al. The role of CXCR3 and its ligands expression in Brucellar spondylitis. Bmc Immunol. 2020 Dec;21(1):1-8Read more>>
  • Xiaoqian Shang. et al. Diagnostic value of CXCR3 and its ligands in spinal tuberculosis. Exp Ther Med. 2021 Jan;21(1):1-1Read more>>
  • Wuchang Zhang. et al. Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress. Mol Cell. 2021 MaRead more>>
  • ing Han. et al. Pulmonary inflammatory and fibrogenic response induced by graphitized multi-walled carbon nanotube involved in cGAS-STING signaling pathway. J Hazard Mater. 2021 May;:125984Read more>>
  • Peng, Cheng. et al. MLKL signaling regulates macrophage polarization in acute pancreatitis through CXCL10. CELL DEATH DIS. 2023 Feb;14(2):1-14Read more>>
  • Chen Chen. et al. Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma. CANCER RES. 2023 JuRead more>>
  • Fenghe Du. et al. Imbalance of helper T cell subtypes and adipokine secretion in perivascular adipose tissue as a trigger of atherosclerosis in chronic Porphyromonas gingivalis W83 infection. MICROBES INFECT. 2023 Jul;:105181Read more>>
  • Maeda Rae. et al. Amino acid catabolite markers for early prognostication of pneumonia in patients with COVID-19. NAT COMMUN. 2023 Dec;14(1):1-17Read more>>
  • Fangyuan Cheng. et al. CSF1R blockade slows progression of cerebral hemorrhage by reducing microglial proliferation and increasing infiltration of CD8?+?CD122+ T cells into the brain. INT IMMUNOPHARMACOL. 2024 May;133:112071Read more>>
  • Luo Wei. et al. Pathoimmunological Analyses of Fatal E11 Infection in Premature Infants. FRONT CELL INFECT MI. 2024 Jul;14Read more>>
  • Zhuo Lili. et al. Integrated immuno-transcriptomic analysis of ovarian cancer identifies a four-chemokine-dominated subtype with antitumor immune-active phenotype and favorable prognosis. BRIT J CANCER. 2024 Aug;:1-12Read more>>
VALIDATION IMAGES