bs-1479R-Cy3 [Conjugated Primary Antibody]
CD80 Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD80

Immunogen Range: 111-265/288


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 941

Swiss Prot: P33681

Source: KLH conjugated synthetic peptide derived from human CD80

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)

Predicted Molecular Weight: 32


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang, Suxin, et al. "Variation and significance of secretory immunoglobulin A, interleukin 6 and dendritic cells in oral cancer." Oncology Letters.Read more>>
  • Gao et al. Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells. (2013) Cell.Transplan. 22:1883-900Read more>>
  • Zheng X et al. Dendritic cells and Th17/Treg ratio play critical roles in pathogenic process of chronic obstructive pulmonary disease. (2018) Biomedicine & Pharmacotherapy.108,1141–1151. Read more>>
  • Xie W et al. Dose Dependent Modulation of Bioactive Glasses Particles on Macrophage and Diabetic Wound Healing. Journal of Materials Chemistry B. 2018.Read more>>
  • Jie Yu. et al. Synergistic enhancement of immunological responses triggered by hyperthermia sensitive Pt NPs via NIR laser to inhibit cancer relapse and metastasis. Bioact Mater. 2021 MayRead more>>
  • Jie Yu. et al. Combining PD-L1 Inhibitors with Immunogenic Cell Death Triggered by Chemo-Photothermal therapy via a Thermosensitive Liposome System to Stimulate Tumor-specific Immunological Response. Nanoscale. 2021 JulRead more>>
  • Liu, Houli. et al. Immunomodulatory hybrid bio-nanovesicle for self-promoted photodynamic therapy. Nano Res. 2022 Feb;:1-1Read more>>
  • Li Yin. et al. G6PD activation in TNBC cells induces macrophage recruitment and M2 polarization to promote tumor progression. CELL MOL LIFE SCI. 2023 Jun;80(6):1-2Read more>>
VALIDATION IMAGES