bs-1456R [Primary Antibody]
Adenosine A2a receptor Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: A2AR/Adenosine A2a receptor

Immunogen Range: 165-300/412


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 135

Swiss Prot: P29274

Source: KLH conjugated synthetic peptide derived from human A2a receptor

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. The encoded protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)

Predicted Molecular Weight: 45


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Cao, Zhi-Ping, et al. "Effects of cordycepin on spontaneous alternation behavior and adenosine receptors expression in hippocampus." Physiology & Behavior (2017).Read more>>
  • Aleix Mart Naviaet al. Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists. Cells. 2020 Jul 21;9(7):1739.Read more>>
  • Junnan Cai. et al. Shufeng Jiedu capsule inhibits inflammation and apoptosis by activating A2AAR and inhibiting NF-B to alleviate LPS-induced ALI. J ETHNOPHARMACOL. 2022 Nov;298:115661Read more>>
  • Xue-qi Liu. et al. Blocking ATP-P1Rs axis attenuate alcohol-related liver fibrosis. LIFE SCI. 2023 Jun;:121896Read more>>
  • Jiajun Chen. et al. Integrating UHPLC-MS/MS quantitative analysis and exogenous purine supplementation to elucidate the antidepressant mechanism of Chaigui granules by regulating purine metabolism. J PHARM ANAL. 2023 AugRead more>>
  • Lv B.. et al. Epoxyeicosatrienoic Acids Attenuate LPS-Induced NIH/3T3 Cell Fibrosis through the A2AR and PI3K/Akt Signaling Pathways. B EXP BIOL MED+. 2024 Aug;:1-5Read more>>
VALIDATION IMAGES

Lane 1:rat heart lysates Lane 2: rat brain lysates probed with Anti A2AR/Adenosine A2a receptor Polyclonal Antibody, Unconjugated (bs-1456R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in RT. Predicted band 64kD. Observed band size: 64kD.


Formalin-fixed and paraffin embedded mouse brain labeled with Anti-A2AR/Adenosine A2a Polyclonal Antibody, Unconjugated (bs-3927R) at 1:200 followed by conjugation to the secondary antibody and DAB staining