bs-1432R-HRP [Conjugated Primary Antibody]
CD68 Polyclonal Antibody, HRP Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD68

Immunogen Range: 1-130/354


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 968

Swiss Prot: P34810

Source: KLH conjugated synthetic peptide derived from human CD68

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Conjugation: HRP

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 37


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Cow

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hu, Kaili, et al. "Lactoferrin conjugated PEG-PLGA nanoparticles for brain delivery: Preparation, characterization and efficacy in Parkinson's disease." International journal of pharmaceutics 415.1 (2011): 273-283.Read more>>
  • Lin, Li-Wen, et al. "Visfatin/pre-B cell colony-enhancing factor immunohistochemical overexpression in oral cancers." Journal of Applied Biomedicine (2014).Read more>>
  • Silva, Katie, et al. "Cortical neurons are a prominent source of the proinflammatory cytokine osteopontin in HIV-associated neurocognitive disorders." Journal of NeuroVirology (2015): 1-12.Read more>>
  • Haoshen Feng. et al. Rosiglitazone ameliorated airway inflammation induced by cigarette smoke via inhibiting the M1 macrophage polarization by activating PPAR and RXR. Int Immunopharmacol. 2021 Aug;97:107809Read more>>
  • Yongxin Guo. et al. Beneficial Effects of Oleosomes Fused with Human Fibroblast Growth Factor 1 on Wound Healing via the Promotion of Angiogenesis. INT J MOL SCI. 2022 Jan;23(21):13152Read more>>
  • Jing Liu. et al. Exosomes Promote Atherosclerosis Progression by Regulating Circ_100696/miR-503-5p/PAPPA Axis-Mediated Vascular Smooth Muscle Cells Proliferation and Migration. INT HEART J. 2023 Sep;64(5):918-927Read more>>
  • Andrea Grandi. et al. A mouse model of progressive lung fibrosis with cutaneous involvement induced by a combination of oropharyngeal and osmotic minipump bleomycin delivery. AM J PHYSIOL-LUNG C. 2024 Apr;(Articles in Press)Read more>>
  • Sahar M Gebril. et al. Effect of Cold Atmospheric Plasma on Hyperglycemia and Immunity in the Spleen of STZ Diabetic Mice. IEEE T RADIAT PLASMA. 2024 Jul;PP(99):1-1Read more>>
VALIDATION IMAGES