bs-13208R-APC

DATASHEET

Host: Rabbit

Target Protein: FOXO4 Thr451

Modification Site: Thr451

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4303

Source: KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Thr451

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

FOXO4 is a forkhead transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. FOXO4 down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 54

Cross Reactive Species: Human
Rat

Predicted Cross Reactive Species: Mouse
Dog
Pig
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.