bs-13195R-A647 [Conjugated Primary Antibody]
Folate Receptor 4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
www.biossusa.com
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Host: Rabbit

Target Protein: Folate Receptor 4

Immunogen Range: 175-225/250


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 390243

Swiss Prot: A6ND01

Source: KLH conjugated synthetic peptide derived from human Folate Receptor 4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Folate receptor 4 is a highly expressed cell surface marker of regulatory T cells. Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for gamete recognition and fertilization. The IZUMO1:FOLR4/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. This receptor does not bind folate.

Conjugation: ALEXA FLUOR® 647

Excitation/ Emission: 650nm/665nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Xiong Lai. et al. Participation of WD repeat-containing protein 54 (WDR54) in rat sperm-oocyte fusion through interaction with both IZUMO1 and JUNO. THERIOGENOLOGY. 2024 Jan;214:286Read more>>