DATASHEET
Host:
Rabbit
Target Protein:
LYVE-1
Immunogen Range:
231-318/318
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
114332
Swiss Prot:
Q8BHC0
Source:
KLH conjugated synthetic peptide derived from mouse LYVE-1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
PRODUCT SPECIFIC PUBLICATIONS
- Hayashi T et al. Characteristics of Leiomyosarcoma: Induction of Hematogenous Metastasis by Isolated Uterine Mesenchymal Tumor Stem-like Cells Anticancer Res. 2020 Mar;40(3):1255-1265.Read more>>
- Zhang, Chun, et al. "MTDH/AEG-1-based DNA vaccine suppresses metastasis and enhances chemosensitivity to paclitaxel in pelvic lymph node metastasis."Biomedicine & Pharmacotherapy (2015).Read more>>
- Michurina et al. Linagliptin alleviates fatty liver disease in diabeticdb/dbmice. (2016) World.J.Diabetes. 7:534-546Read more>>
- Merigo et al. Glucose transporter expression in the human colon. (2018) World.J.Gastroenterol. 24:775-793Read more>>
- Hayashi T et al. Characteristics of Leiomyosarcoma: Induction of Hematogenous Metastasis by Isolated Uterine Mesenchymal Tumor Stem-like Cells Anticancer Res. 2020 Mar;40(3):1255-1265.Read more>>
- Tashiro Kensuke. et al. Extracellular vesicles from adipose-derived stem cells relieve extremity lymphedema in mouse models.. PLAST RECONSTR SURG. 2023 Mar;:10.1097/PRS.0000000000010388Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human breast cancer tissue labeled with Anti-LYVE-1 Polyclonal Antibody, Unconjugated (bs-1311R) followed by conjugation to the secondary antibody and DAB staining
Lane 1: Mouse Liver tissue lysates; Lane 2: Mouse Spleen tissue lysates; Lane 3: Human Huvec cell lysates; Lane 4: Human K562 cell lysates probed with LYVE-1 Polyclonal Antibody, Unconjugated (bs-1311R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.