DATASHEET
Host:
Rabbit
Target Protein:
HLA E
Immunogen Range:
251-358/358
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
3133
Swiss Prot:
P13747
Source:
KLH conjugated synthetic peptide derived from human HLA E
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
HLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.
PRODUCT SPECIFIC PUBLICATIONS
- Sun et al. High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer. (2017) Oncoimmunology. 6:e1264562Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin-embedded human rectal carcinoma labeled with Rabbit Anti-HLA-E Polyclonal Antibody (bs-1279R), Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin-embedded human rectal carcinoma labeled with Rabbit Anti-HLA-E Polyclonal Antibody (bs-1279R), Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining
Raji cell lysates probed with Rabbit Anti-HLA E Polyclonal Antibody (bs-1279R) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody (bs-0295G-HRP ) at 1:5000 for 90 min at 37˚C.