bs-12125R [Primary Antibody]
SLC38A2/SNAT2 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SLC38A2/SNAT2

Immunogen Range: 21-150/506


Clonality: Polyclonal

Isotype: IgG

Swiss Prot: Q96QD8

Source: KLH conjugated synthetic peptide derived from human SLC38A2/SNAT2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT2, also designated ATA2, PRO1068 and SAT2 is encoded by the human gene SLC38A2. The functional role of SNAT2 in the nervous system is unclear. Protein expression is notably enriched in the spinal cord and brain stem nuclei of the auditory system. System A transport proteins are also present in placental tissue. These SNAT proteins may play a significant role in fetal development and inhibition of the transport system has been associated with fetal growth retardation.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 56


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Sheep
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hu C et al. Placentae for Low Birth Weight Piglets Are Vulnerable to Oxidative Stress, Mitochondrial Dysfunction, and Impaired Angiogenesis. Oxid Med Cell Longev. 2020 May 25;2020:8715412.Read more>>
  • Jan Remsik. et al. Characterization, isolation and in vitro culture of leptomeningeal fibroblasts. J Neuroimmunol. 2021 Sep;:577727Read more>>
  • Zhao Xiaohui. et al. Chemoproteomics reveals microbiota-derived aromatic monoamine agonists for GPRC5A. NAT CHEM BIOL. 2023 May;:1-1Read more>>
  • Mingzhi Xia. et al. miR-10b-5p promotes tumor growth by regulating cell metabolism in liver cancer via targeting SLC38A2. CANCER BIOL THER. 2024 Feb 23Read more>>
  • Jiang Tingting. et al. SNAT2-mediated regulation of estrogen and progesterone in the proliferation of goat mammary epithelial cells. AMINO ACIDS. 2024 Dec;56(1):1-12Read more>>
  • Kui Wu. et al. SLC38A2 promotes cell proliferation and invasion by promoting glutamine metabolism in adenomyosis. EXP THER MED. 2024 May;27(5):1-9Read more>>
  • Xiaoyue Ma. et al. Prolactin Modulates the Proliferation and Secretion of Goat Mammary Epithelial Cells via Regulating Sodium-Coupled Neutral Amino Acid Transporter 1 and 2. CELLS-BASEL. 2024 Jan;13(17):1461Read more>>
VALIDATION IMAGES

Paraformaldehyde-fixed, paraffin embedded mouse small intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with SLC38A2 Polyclonal Antibody, Unconjugated (bs-12125R) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining.


Mouse intestine lysates probed with SLC38A2 Polyclonal Antibody, Unconjugated (bs-12125R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.


Lane 1: Mouse Liver tissue lysates; Lane 2: Rat Lung tissue lysates probed with SLC38A2 Polyclonal Antibody, Unconjugated (bs-12125R) at 1:200 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.