bs-11962R-BF555

DATASHEET

Host: Rabbit

Target Protein: SNAIL + SLUG Ser246

Modification Site: Ser246

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6311

Swiss Prot: O95863

Source: KLH conjugated synthetic phosphopeptide derived from human SNAIL around the phosphorylation site of Ser246

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin. SLUG is involved in epithelial-mesenchymal transitions (EMT) involving E-cadherin repression which is known to play an important role in tumor progression amd neural tube formation. SLUG also has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects (referenced from Entrez gene).

Conjugation: AbBy Fluor® 555

Excitation/ Emission: 553nm/568nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)

Predicted Molecular Weight: 29

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.