DATASHEET
Host:
Rabbit
Target Protein:
POMC
Immunogen Range:
237-267/267
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
5443
Swiss Prot:
P01189
Source:
KLH conjugated synthetic peptide derived from human POMC
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.
PRODUCT SPECIFIC PUBLICATIONS
- Chao, Po-Kuan, et al. ʺEarly Systemic Granulocyte-Colony Stimulating Factor Treatment Attenuates Neuropathic Pain after Peripheral Nerve Injury.ʺ PloS one 7.8 (2012): e43680.Read more>>
- Nakamoto, Kazuo, et al. ʺHypothalamic GPR40 Signaling Activated by Free Long Chain Fatty Acids Suppresses CFA-Induced Inflammatory Chronic Pain.ʺ PLOS ONE 8.12 (2013): e81563.Read more>>
- Xie, Fang, et al. "Early Repeated Administration of CXCR4 Antagonist AMD3100 Dose-Dependently Improves Neuropathic Pain in Rats After L5 Spinal Nerve Ligation." Neurochemical Research (2016): 1-11.Read more>>
- Tzu-Kai Lin. et al. Low-concentration imiquimod treatment promotes enhanced skin barrier functions through epidermal melanization reaction regulation. ENVIRON TOXICOL. 2024 MayRead more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded mouse tumor labeled with Anti-β-endorphin Polyclonal Antibody, Unconjugated (bs-1195R) followed by conjugation to the secondary antibody and DAB staining
Paraformaldehyde-fixed, paraffin embedded Mouse hypophysis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with POMC Polyclonal Antibody, Unconjugated (bs-1195R) at 1:400 overnight at 4°C, DAB staining.