bs-11841R-BF750

DATASHEET

Host: Rabbit

Target Protein: FNBP1L/TOCA1

Immunogen Range: 101-200/605

Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated synthetic peptide derived from human FNBP1L/TOCA1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Conjugation: AbBy Fluor® 750

Excitation/ Emission: 749nm/775nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 70

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Cow
Sheep
Pig
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.