bs-1157R [Primary Antibody]
Fibrillin 1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Fibrillin 1

Immunogen Range: 401-500/2872


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2200

Swiss Prot: P35555

Source: KLH conjugated synthetic peptide derived from human FBN1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 316


Cross Reactive Species: Human
Rat

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Farrell K et al. Alterations in phenotype and gene expression of adult human aneurysmal smooth muscle cells by exogenous nitric oxide. Exp Cell Res. 2019 Nov 1;384(1):111589. Read more>>
  • Seita Morishita. et al. Expression of Lymphatic Markers in the Bergers Space and Bursa Premacularis. Int J Mol Sci. 2021 Jan;22(4):2086Read more>>
  • Shun Nonoyama. et al. Development and Characterization of Alkaline Phosphatase-Positive Human Umbilical Cord Perivascular Cells. Cells-Basel. 2021 Nov;10(11):3011Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human placenta labeled with Anti-FBN1/fibrillin 1 Polyclonal Antibody, Unconjugated (bs-1157R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.


Formalin-fixed and paraffin embedded Rat liver labeled with Anti-FBN1/fibrillin 1 Polyclonal Antibody, Unconjugated (bs-1157R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.