DATASHEET
Host:
Rabbit
Target Protein:
ATP1b2/Na+K+ATPase
Immunogen Range:
201-290/290
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
482
Swiss Prot:
P14415
Source:
KLH conjugated synthetic peptide derived from human ATP1b2
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
PRODUCT SPECIFIC PUBLICATIONS
- Wang HY et al. Occludin Endocytosis is Involved in Disruption of the Intestinal Epithelial Barrier in a Mouse Model of Alcoholic Steatohepatitis. J Dig Dis. 2019 Jul 12. Read more>>
- Shiman Zuo. et al. Establishment of a novel mesenchymal stem cell-based regimen for chronic myeloid leukemia differentiation therapy. Cell Death Dis. 2021 Feb;12(2):1-15Read more>>
- Sun, Zeguo. et al. LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer. MOL CANCER. 2022 Dec;21(1):1-24Read more>>
- Yanhui Jia. et al. The deacetylation of Akt by SIRT1 inhibits inflammation in macrophages and protects against sepsis. EXP BIOL MED. ;()Read more>>
VALIDATION IMAGES
L1 rat kidney lysates L2 rat colon lysates probed with Anti ATP1b2/Na+K+ATPase Polyclonal Antibody, Unconjugated (bs-1152R) at 1:200 overnight at 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 for 90 min at RT. Predicted band 33kD. Observed band size: 33kD.
Lane 1: Mouse Cerebrum tissue lysates; Lane 2: Human K562 cell lysates; Lane 3: Human SH-SY5Y cell lysates probed with ATPase Na+/ K+ beta 2 Polyclonal Antibody, Unconjugated (bs-1152R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.