bs-1151R-BF488 [Conjugated Primary Antibody]
TRBF1/TRF1 Polyclonal Antibody, AbBy Fluor® 488 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: TRBF1/TRF1

Immunogen Range: 121-220/439


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7013

Source: KLH conjugated synthetic peptide derived from human TRBF1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq].

Conjugation: AbBy Fluor® 488

Excitation/ Emission: 499nm/519nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 50


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Esra Gozde Kosebent et al. The altered expression of telomerase components and telomere-linked proteins may associate with ovarian aging in mouse. Exp Gerontol. 2020 Sep;138:110975.Read more>>
  • Esra G. Kosebent. et al. The spatiotemporal expression of TERT and telomere repeat binding proteins in the postnatal mouse testes. 2021 Feb 05Read more>>
  • Fatma Uysal. et al. Decreased expression of TERT and telomeric proteins as human ovaries age may cause telomere shortening. J Assist Reprod Gen. 2021 Feb;38(2):429-441Read more>>
  • Xiaoyu Qi. et al. Curcumol inhibits ferritinophagy to restrain hepatocyte senescence through YAP/NCOA4 in non-alcoholic fatty liver disease. 2021 Aug 03Read more>>
  • Jiang, Yiming. et al. Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy. 2021 Aug 17Read more>>
  • Qi Xiaoyu. et al. Curcumol Suppresses CCF-Mediated Hepatocyte Senescence Through Blocking LC3BLamin B1 Interaction in Alcoholic Fatty Liver Disease. FRONT PHARMACOL. 2022 Jun;0:214Read more>>
  • Chunfeng Lu. et al. ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2-stabilized?PINK1/Parkin-mediated mitophagy. CELL PROLIFERAT. 2022 Dec;:e13378Read more>>