bs-11397R-BF350 [Conjugated Primary Antibody]
Arginase 2 Polyclonal Antibody, AbBy Fluor® 350 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Arginase 2

Immunogen Range: 181-290/354


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 384

Swiss Prot: P78540

Source: KLH conjugated synthetic peptide derived from human Arginase II

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

Conjugation: AbBy Fluor® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 36


Cross Reactive Species: Human
Mouse
Sheep

Predicted Cross Reactive Species: Rat
Dog
Cow
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zaytouni et al. Critical role for arginase 2 in obesity-associated pancreatic cancer. (2017) Nat.Commun. 8:242Read more>>
  • Liu Y et al. Isolation and characterization of ovine monocyte-derived macrophages from peripheral blood.(2018)Vet Immunol Immunopathol. Nov;205:83-92. Read more>>
  • Aihara Seishi. et al. Spermidine from arginine metabolism activates Nrf2 and inhibits kidney fibrosis. COMMUN BIOL. 2023 Jun;6(1):1-14Read more>>
  • Imazu Noriyuki. et al. Arginase 2 attenuates ulcerative colitis by antioxidant effects of spermidine. J GASTROENTEROL. 2024 May;:1-17Read more>>
VALIDATION IMAGES