bs-1110R-PE
[Conjugated Primary Antibody]
Osterix Polyclonal Antibody, PE Conjugated
DATASHEET
Host: Rabbit
Target Protein: Osterix
Immunogen Range: 331-431/431
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 121340
Swiss Prot: Q8TDD2
Source: KLH conjugated synthetic peptide derived from human Osterix
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity).
Conjugation: PE
Excitation/ Emission: 496,564nm/578nm
Size: 100ul
Concentration: 1ug/ul
Applications: WB(1:300-5000)
Predicted Molecular Weight: 45
Cross Reactive Species:
Human
Mouse
Rabbit
Predicted Cross Reactive Species:
Rat
Dog
Cow
Pig
Horse
For research use only. Not intended for diagnostic or therapeutic use.
PRODUCT SPECIFIC PUBLICATIONS
- Chen, Jin‐Ran, et al. "Diet derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice." Journal of Bone and Mineral Research (2013).Read more>>
- Dong, Weijie, et al. "Phenotypic characterization of craniofacial bone marrow stromal cells: unique properties of enhanced osteogenesis, cell recruitment, autophagy, and apoptosis resistance." Cell and Tissue Research (2014): 1-11.Read more>>
- Kishi, Yuta, et al. "PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway."International Journal of Molecular Sciences 16.10 (2015): 24820-24838.Read more>>
- Agarwal, Shailesh, et al. "Analysis of bone‐cartilage‐stromal progenitor populations in trauma induced and genetic models of heterotopic ossification." STEM CELLS (2016).Read more>>
- Tang, Zhurong, et al. "Comparison of ectopic bone formation process induced by four calcium phosphate ceramics in mice." Materials Science and Engineering: C (2016).Read more>>
- Schlie-Wolter, S., et al. Osteogenic Differentiation of Human Adipose-Derived Stem Cells (hASC): Role of FAK and Ras-MAPK Signaling. (2016) J Stem Cell Regen Bio 2(2): 1- 19Read more>>
- Agarwal, Shailesh, et al. "Local and Circulating Endothelial Cells Undergo Endothelial to Mesenchymal Transition (EndMT) in Response to Musculoskeletal Injury." Scientific Reports 6 (2016): 32514.Read more>>
- Rajshankar, Dhaarmini, Yongqiang Wang, and Christopher A. McCulloch. "Osteogenesis requires FAK-dependent collagen synthesis by fibroblasts and osteoblasts." The FASEB Journal (2016): fj-201600645R.Read more>>
- Wang, Yilin, et al. "Synergistic effects of overexpression of BMP‑2 and TGF‑β3 on osteogenic differentiation of bone marrow mesenchymal stem cells." Molecular Medicine Reports (2016): 11.Read more>>
- Ranganathan, Kavitha, et al. "The role of the adaptive immune system in burn-induced heterotopic ossification and mesenchymal cell osteogenic differentiation." Journal of Surgical Research 206.1 (2016): 53-61.Read more>>
- Li, Shao, et al. "A Conditional Knockout Mouse Model Reveals a Critical Role of PKD1 in Osteoblast Differentiation and Bone Development." Scientific Reports 7 (2017): 40505.Read more>>
- Qian, Dong-Yang, et al. "Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells." Biomedicine & Pharmacotherapy 90 (2017): 492-499.Read more>>
- Shi, Hua-Li, et al. "Effect of polygonimitin C on bone formation and resorption in human osteoblast-like MG63 cells." Tropical Journal of Pharmaceutical Research 16.7 (2017): 1595-1600.Read more>>
- Chen et al. Diet derived phenolic acids regulate osteoblast and adipocyte lineage commitment and differentiation in young mice. (2013) J.Bone.Miner.Res. Read more>>
- Agarwal et al. Analysis of Bone-Cartilage-Stromal Progenitor Populations in Trauma Induced and Genetic Models of Heterotopic Ossification. (2016) Stem.Cells. 34:1692-701Read more>>
- Bihari C et al. Suboptimal Level of Bone-Forming Cells in Advanced Cirrhosis are Associated with Hepatic Osteodystrophy. (2018) Hepatol Commun.Sep 4;2(9):1095-1110.Read more>>
- Cui Q et al. Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway. Cell Death Dis. 2019 Feb 20;10(3):172. Read more>>
- Chang Z et al. Reticulocalbin 2 enhances osteogenic differentiation of human vascular smooth muscle cells in diabetic conditions. Life Sci. 2019 Sep 15;233:116746.Read more>>
- Yong Tang. et al. Phosphorylation inhibition of protein-tyrosine phosphatase 1B tyrosine-152 induces bone regeneration coupled with angiogenesis for bone tissue engineering. Bioact Mater. 2021 Jul;6:2039Read more>>
- Yongkui Wang. et al. Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3/-catenin signaling. Toxicol Appl Pharm. 2020 Dec;409:115333Read more>>
- o Zhang. et al. Neuropeptide?Y upregulates Runx2 and osterix and enhances osteogenesis in mouse MC3T3?E1 cells via an autocrine mechanism. Mol Med Rep. 2020 Nov;22(5):4376-4382Read more>>
- Yong Tang. et al. Laminin alpha 4 promotes bone regeneration by facilitating cell adhesion and vascularization. Acta Biomater. 2021 MaRead more>>
- Yu-Ting Yen. et al. PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Commun Biol. 2021 Jun;4(1):1-12Read more>>
- Kohei Arakawa. et al. The difference in joint instability affects the onset of cartilage degeneration or subchondral bone changes. Osteoarthr Cartilage. 2021 DecRead more>>
- Zhao, Gang. et al. LINC02381, a sponge of miR-21, weakens osteogenic differentiation of hUC-MSCs through KLF12-mediated Wnt4 transcriptional repression. 2021 Nov 15Read more>>
- Rui Zhang. et al. Multifunctional silicon calcium phosphate composite scaffolds promote stem cell recruitment and bone regeneration. J MATER CHEM B. 2022 JuRead more>>
- Song Xiaoliang. et al. Bioinspired Protein/Peptide Loaded 3D Printed PLGA Scaffold Promotes Bone Regeneration. FRONT BIOENG BIOTECH. 2022 Jul;0:1195Read more>>
- Jiarui Lu. et al. Injectable Col-_/CS hydrogel enhances bone regeneration in mice tibial mono-cortical defect with impaired osteogenesis. MATER TODAY COMMUN. 2022 Aug;32:10407Read more>>
- Jingyuan Wen. et al. Qiangguyin inhibited fat accumulation in OVX mice through the p38 MAPK signaling pathway to achieve anti-osteoporosis effects. BIOMED PHARMACOTHER. 2023 Feb;158:114122Read more>>
- ?brahim Halilullah Erbay. et al. Bioengineering bone-on-a-chip model harnessing osteoblastic and osteoclastic resolution. ADV ENG MATER. 2022 DecRead more>>
- Xiaoxia Hao. et al. Bone deterioration in response to chronic high-altitude hypoxia is attenuated by a pulsed electromagnetic field via the primary cilium/HIF-1 axis. J BONE MINER RES. 2023 JaRead more>>
- Hongrong Zhang. et al. Extracellular matrix of ameloblastoma-derived negatively regulates osteogenic differentiation. ORAL DIS. 2023 JulRead more>>
- Wang Liu. et al. Yunnan Baiyao Might Mitigate Periodontitis Bone Destruction by Inhibiting Autophagy and Promoting Osteoblast Differentiation in vivo, ex vivo and in vitro. J INFLAMM RES. 2024 Apr 14Read more>>
- Dan Wang. et al. Gut microbial alterations in arginine metabolism determine bone mechanical adaptation. CELL METAB. 2024 07Read more>>
- Chen Xinping. et al. mPPTMP195 nanoparticles enhance fracture recovery through HDAC4 nuclear translocation inhibition. J NANOBIOTECHNOL. 2024 Dec;22(1):1-18Read more>>
- Enzhao Shen. et al. CMTM3 Suppresses Proliferation and Osteogenic Transdifferentiation of C2C12 Myoblasts through p53 Upregulation. CELLS-BASEL. 2024 Jan;13(16):1352Read more>>
- Chen Chongwei. et al. LMK-235 suppresses osteoclastogenesis and promotes osteoblastogenesis by inhibiting HDAC4. SCI REP-UK. 2024 Aug;14(1):1-15Read more>>
VALIDATION IMAGES