bs-1095R-PE [Conjugated Primary Antibody]
Orexin receptor 1+2 Polyclonal Antibody, PE Conjugated
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: Orexin receptor 1+2

Immunogen Range: 321-425/444


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3062

Swiss Prot: O43614

Source: KLH conjugated synthetic peptide derived from human Orexin receptor 1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]

Conjugation: PE

Excitation/ Emission: 496,564nm/578nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 50


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hui Fenget al. Orexin signaling modulates synchronized excitation in the sublaterodorsal tegmental nucleus to stabilize REM sleep. Nat Commun. 2020 Jul 21;11(1):3661.Read more>>
  • Qi-Cheng Qiao. et al. Orexin recruits non-selective cationic conductance and endocannabinoid to dynamically modulate firing of caudal pontine reticular nuclear neurones. J PHYSIOL-LONDON. 2023 JulRead more>>
VALIDATION IMAGES