bs-1090C
[Life Science]
Tasisulam(LY573636)
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 415.11
Formula: C11 H6 Br Cl2 N O3 S2
CAS Number: 519055-62-0
InChi Key: WWONFUQGBVOKOF-UHFFFAOYSA-N
InChi: InChI=1S/C11H6BrCl2NO3S2/c12-9-3-4-10(19-9)20(17,18)15-11(16)7-2-1-6(13)5-8(7)14/h1-5H,(H,15,16)
Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1C=CC(Cl)=CC=1Cl
Purity: 98.0
Solubility: DMSO: 77 mg/mL (185.5 mM) Ethanol: 77 mg/mL (185.5 mM) Water: <1 mg/mL
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C11 H6 Br Cl2 N O3 S2
CAS Number: 519055-62-0
InChi Key: WWONFUQGBVOKOF-UHFFFAOYSA-N
InChi: InChI=1S/C11H6BrCl2NO3S2/c12-9-3-4-10(19-9)20(17,18)15-11(16)7-2-1-6(13)5-8(7)14/h1-5H,(H,15,16)
Smiles: O=C(NS(=O)(=O)C1=CC=C(Br)S1)C1C=CC(Cl)=CC=1Cl
Purity: 98.0
Solubility: DMSO: 77 mg/mL (185.5 mM) Ethanol: 77 mg/mL (185.5 mM) Water: <1 mg/mL
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
Tasisulam, also known as LY573636, is an acyl-sulfonamide with potential antineoplastic activity. Selectively toxic towards tumor cells, tasisulam appears to induce tumor cell apoptosis by a mitochondrial-targeted mechanism involving the loss of mitochondrial membrane potential and induction of reactive oxygen species (ROS). In combination with an angiogenesis inhibitor, this agent may exhibit synergistic antiangiogenic activity.
Size: 2 mg solid, 10mg solid2 mg solid, 10mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.