bs-1080C
[Life Science]
S1RA hydrochloride
DATASHEET
Formulation Powder
Storage: Store in dry, dark place at -20C for 1 year.
Product Information:
Molecular Weight: 373.88
Formula: C20 H24 Cl N3 O2
CAS Number: 1265917-14-3
InChi Key: SHRYQZBTQDMGLZ-UHFFFAOYSA-N
InChi: InChI=1S/C20H23N3O2.ClH/c1-16-14-20(25-13-10-22-8-11-24-12-9-22)21-23(16)19-7-6-17-4-2-3-5-18(17)15-19;/h2-7,14-15H,8-13H2,1H3;1H
Smiles: Cl.CC1=CC(=NN1C1=CC2=CC=CC=C2C=C1)OCCN1CCOCC1
Purity: 98.0
Solubility: DMSO: ‚â• 57 mg/mL
Appearance: Solid Power
Shelf Life: 1.0 years
Formula: C20 H24 Cl N3 O2
CAS Number: 1265917-14-3
InChi Key: SHRYQZBTQDMGLZ-UHFFFAOYSA-N
InChi: InChI=1S/C20H23N3O2.ClH/c1-16-14-20(25-13-10-22-8-11-24-12-9-22)21-23(16)19-7-6-17-4-2-3-5-18(17)15-19;/h2-7,14-15H,8-13H2,1H3;1H
Smiles: Cl.CC1=CC(=NN1C1=CC2=CC=CC=C2C=C1)OCCN1CCOCC1
Purity: 98.0
Solubility: DMSO: ‚â• 57 mg/mL
Appearance: Solid Power
Shelf Life: 1.0 years
Description:
E-52862, also known as S1RA and MR390, is a selective sigma-1 receptor antagonist, with a reported binding affinity of Ki = 17.0 ± 7.0 nM, selective over the sigma-2 receptor and against a panel of other 170 receptors, enzymes, transporters and ion channels. In preclinical studies, S1RA has demonstrated efficacy in relieving neuropathic pain and pain in other sensitizing conditions, associated with an improvement of the emotional negative state. E-52862 attenuates neuropathic pain of different aetiology in rats.
Size: 10mg solid,2mg solid 10mg solid,2mg solid
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.