DATASHEET
Host:
Rabbit
Target Protein:
Sialoadhesin
Immunogen Range:
851-950/1709
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
6614
Swiss Prot:
Q9BZZ2
Source:
KLH conjugated synthetic peptide derived from human Sialoadhesin
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis.
PRODUCT SPECIFIC PUBLICATIONS
- Antonia RuJia Sun. et al. Effects of Diet Induced Weight Reduction on Cartilage Pathology and Inflammatory Mediators in the Joint Tissues. Front Med-Lausanne. 2021; 8: 628843Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human glioma tissue labeled with Anti-Sialoadhesin Polyclonal Antibody, Unconjugated (bs-10751R) at 1:300 followed by conjugation to the secondary antibody (bs-0295G-HRP) and DAB staining.
Formalin-fixed and paraffin embedded rat spleen labeled with Anti-Sialoadhesin Polyclonal Antibody, Unconjugated (bs-10751R) at 1:500 followed by conjugation to the secondary antibody and DAB staining.
Formalin-fixed and paraffin embedded rat spleen labeled with Anti-Sialoadhesin Polyclonal Antibody, Unconjugated (bs-10751R) at 1:500 followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin embedded rat lung labeled with Anti-Sialoadhesin Polyclonal Antibody, Unconjugated (bs-10751R) at 1:500 followed by conjugation to the secondary antibody and DAB staining
U937 cells probed with Rabbit Anti-Sialoadhesin Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated (bs-10751R-A647) for 30 minutes compared to control cells (blue) and isotype control (orange).