bs-10721R-PE [Conjugated Primary Antibody]
Histone H4 (Acetyl K5) Polyclonal Antibody, PE Conjugated
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: Histone H4 (Acetyl K5)

Modification Site: K5

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 121504

Swiss Prot: P02304

Source: KLH conjugated synthetic peptide derived from human Histone H4 (Acetyl K5)

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Jul 2008].

Conjugation: PE

Excitation/ Emission: 496,564nm/578nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 11


Cross Reactive Species: Rat

Predicted Cross Reactive Species: Human
Mouse
Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yinjie Lian. et al. Histone Chaperone Nrp1 Mutation Affects the Acetylation of H3K56 in Tetrahymena thermophila. Cells-Basel. 2022 Jan;11(3):408Read more>>
  • Wang Hao. et al. Histone acetylation by HBO1 (KAT7) activates Wnt/-catenin signaling to promote leukemogenesis in B-cell acute lymphoblastic leukemia. CELL DEATH DIS. 2023 Aug;14(8):1-14Read more>>
VALIDATION IMAGES