bs-10332R-BF555 [Conjugated Primary Antibody]
VGF/NERP2 Polyclonal Antibody, AbBy Fluor® 555 Conjugated
www.biossusa.com
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Host: Rabbit

Target Protein: VGF/NERP2

Immunogen Range: 301-400/615


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7425

Swiss Prot: O15240

Source: KLH conjugated synthetic peptide derived from human NERP2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. Nerve growth factor (NGF) is a peptide that plays a key role in the differentiation and survival of neurons in the peripheral nervous system (PNS) and the central nervous system (CNS). VGF is a peptide synthesized and secreted by neurons and is upregulated by NGF in the PC12 cell line. VGF is widely expressed in both the PNS and CNS, but is especially abundant in the adult hypothalamus. VGF plays an essential role in how the brain regulates energy expenditure and body weight. Its expression is rapidly induced by injury, the circadian clock, and neuronal activity.

Conjugation: AbBy Fluor® 555

Excitation/ Emission: 553nm/568nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 4.2/65


Cross Reactive Species: Zebrafish

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.