DATASHEET
Host:
Rabbit
Target Protein:
HMGA1
Immunogen Range:
51-107/107
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
3159
Swiss Prot:
P17096
Source:
KLH conjugated synthetic peptide derived from human HMGA1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
PRODUCT SPECIFIC PUBLICATIONS
- Uchikura, Yuka, et al. "Extranuclear Translocation of High-Mobility Group A1 Reduces the Invasion of Extravillous Trophoblasts Involved in the Pathogenesis of Preeclampsia: New Aspect of High-Mobility Group A1." Reproductive Sciences (2017): 1933719117697254.Read more>>
- Jiang, Yiming. et al. Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy. 2021 Aug 17Read more>>
- Wang Shidong. et al. LncRNA CASC19 promotes gastric cancer progression through preventing CREB1 protein ubiquitin/proteasome-dependent degradation. CARCINOGENESIS. 2023 JaRead more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-HMGA1/HMG-I/HMG-Y Polyclonal Antibody, Unconjugated (bs-1030R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Formalin-fixed and paraffin embedded human glioma labeled with Anti-HMGA1/HMG-I/HMG-Y Polyclonal Antibody, Unconjugated (bs-1030R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.