Host: Rabbit
Target Protein: Sclerostin
Immunogen Range: 121-180/213
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 50964
Swiss Prot: Q9BQB4
Source: KLH conjugated synthetic peptide derived from human Sclerostin
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Conjugation: Cy3
Excitation/ Emission: 512,550nm/570,615nm
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Predicted Molecular Weight: 21
Cross Reactive Species:
Human
Mouse
Rat
Rabbit
Predicted Cross Reactive Species:
Dog
Cow
Sheep
Pig
Horse
For research use only. Not intended for diagnostic or therapeutic use.
- Diao et al. The Microdamage and Expression of Sclerostin in Peri-implant Bone under One-time Shock Force Generated by Impact. (2017) Sci.Rep. 7:6508Read more>>
- Surowiec RK et al. A Xenograft Model to Evaluate the Bone Forming Effects of Sclerostin Antibody in Human Bone Derived from Pediatric Osteogenesis Imperfecta Patients. Bone. 2020 Jan;130:115118.Read more>>
- Zhang C et al. FOXO1 Mediates Advanced Glycation End Products Induced Mouse Osteocyte-Like MLO-Y4 Cell Apoptosis and Dysfunctions. Journal of Diabetes Research.2019, Article ID 6757428.Read more>>
- Yiqi Yanget al. Bioprinting of an osteocyte network for biomimetic mineralization. Biofabrication. 2020 Jul 29;12(4):045013.Read more>>
- Yoo-Sung Nam. et al. Sclerostin in Periodontal Ligament: Homeostatic Regulator in Biophysical Force-Induced Tooth Movement. J CLIN PERIODONTOL. 2022 Apr 03Read more>>
- Young Jae Moon. et al. Sirtuin 6 Overexpression Improves Rotator Cuff Tendon-to-Bone Healing in the Aged. CELLS-BASEL. 2023 Jan;12(16):2035Read more>>
- Chen Shengqiang. et al. Local H2 release remodels senescence microenvironment for improved repair of injured bone. NAT COMMUN. 2023 Nov;14(1):1-16Read more>>
- Wyonna Darleen Rindt. et al. A 3D bioreactor model to study osteocyte differentiation and mechanobiology under perfusion and compressive mechanical loading. ACTA BIOMATER. 2024 Aug;184:21Read more>>