bs-10132R [Primary Antibody]
Integrin alpha 2/CD49b Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Integrin alpha 2/CD49b

Immunogen Range: 801-900/1181


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3673

Swiss Prot: P17301

Source: KLH conjugated synthetic peptide derived from human Integrin alpha 2/CD49b

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
ICC(1:100-500)

Predicted Molecular Weight: 127


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wang et al. Loss of calponin h1 confers anoikis resistance and tumor progression in the development of high-grade serous carcinoma originating from the fallopian tube epithelium. (2017) Oncotarget. 8:61133-61146Read more>>
VALIDATION IMAGES

293T(Human) Cell Lysate at 30 ug probed with Integrin alpha 2/CD49b Polyclonal Antibody (bs-10132R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.