bs-10067R-Cy7 [Conjugated Primary Antibody]
SP-C Polyclonal Antibody, Cy7 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SP-C

Immunogen Range: 24-58/197


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6440

Swiss Prot: P11686

Source: KLH conjugated synthetic peptide derived from human SP-C

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 21-Apr


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Cow
Sheep
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Vadasz, Stephanie, et al. "Second and third trimester amniotic fluid mesenchymal stem cells can repopulate a de-cellularized lung scaffold and express lung markers." Journal of Pediatric Surgery (2014).Read more>>
  • Mitchell A et al. Human induced pluripotent stem cells ameliorate hyperoxia-induced lung injury in a mouse model. Am J Transl Res. 2020 Jan 15;12(1):292-307.Read more>>
  • Dinh, Phuong-Uyen C., et al. "Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies." Respiratory Research 18.1 (2017): 132.Read more>>
  • Mitchell, Adam, et al. "Production of high purity alveolar-like cells from iPSCs through depletion of uncommitted cells after AFE induction." Differentiation(2017).Read more>>
  • Yang et al. CXCR4 receptor overexpression in mesenchymal stem cells facilitates treatment of acute lung injury in rats. (2015) J.Biol.Chem. 290:1994-2006Read more>>
  • Ding et al. Glycogen synthase kinase‑3β inhibitor reduces LPS‑induced acute lung injury in mice. (2017) Mol.Med.Rep. 16:6715-6721Read more>>
  • Liu T et al. Telomerase reverse transcriptase ameliorates lung fibrosis by protecting alveolar epithelial cells against senescence. J Biol Chem. 2019 Apr 18. pii: jbc.RA118.006615. Read more>>
  • Kerr NA et al. Human Lung Cell Pyroptosis Following Traumatic Brain Injury. Cells. 2019 Jan 18;8(1). pii: E69.Read more>>
  • Mitchell A et al. Assessment of iPSC Teratogenicity throughout Directed Differentiation toward an Alveolar-like Phenotype. Differentiation. 2019 Jan - Feb;105:45-53. Read more>>
  • Mitchell A et al. Human induced pluripotent stem cells ameliorate hyperoxia-induced lung injury in a mouse model. Am J Transl Res. 2020 Jan 15;12(1):292-307.Read more>>
  • Aschner Y et al. Protein Tyrosine Phosphatase- Amplifies TGF--Dependent Pro-Fibrotic Signaling in Lung Fibroblasts. American Journal of Physiology-Lung Cellular and Molecular Physiology. 2020.Read more>>
  • Liu X. et al. Effects of Different Ligands in the Notch Signaling Pathway on the Proliferation and Transdifferentiation of Primary Type II Alveolar Epithelial Cells.. Front Pediatr. 2020 Aug;8:452-452Read more>>
  • Naoya Kawakita. et al. Bronchioalveolar stem cells derived from mouse-induced pluripotent stem cells promote airway epithelium regeneration. Stem Cell Res Ther. 2020 Dec;11(1):1-14Read more>>
  • Jer-Hwa Chang. et al. Air pollution-regulated E-cadherin mediates contact inhibition of proliferation via the hippo signaling pathways in emphysema. Chem-Biol Interact. 2022 Jan;351:109763Read more>>
  • Shota Mitsuboshi. et al. A novel alveolar epithelial cell sheet fabricated under feeder-free conditions for potential use in pulmonary regenerative therapy. Regen Ther. 2022 Mar;19:113Read more>>
  • Lei Chen. et al. MiR-199a-3p in mouse bone marrow mesenchymal stem cell exosomes increases epithelial sodium channel expression in lung injury. FUND CLIN PHARMACOL. 2022 Jun 1Read more>>
  • Lei Chen. et al. Luteolin Enhances Transepithelial Sodium Transport in the Lung Alveolar Model: Integrating Network Pharmacology and Mechanism Study. INT J MOL SCI. 2023 Jan;24(12):10122Read more>>