Host: Rabbit
Target Protein: KLRK1
Immunogen Range: 121-219/219
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 24934
Swiss Prot: O70215
Source: KLH conjugated synthetic peptide derived from rat KLRK1
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Predicted Molecular Weight: 25
Cross Reactive Species: Mouse
Predicted Cross Reactive Species:
Human
Rat
For research use only. Not intended for diagnostic or therapeutic use.
- Long Y et al. Downregulation of MCT 4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma.Cancer Med. 2018 Sep;7(9):4690-4700. Read more>>
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- Onishi,Hideya, et al. "Random Migration Contributes to Cytotoxicity of Activated CD8+ T-Lymphocytes But Not NK cells." Anticancer Research 34.8 (2014): 3947-3956.Read more>>
- Song et al. Synergistic anti-tumor effects of dasatinib and dendritic cell vaccine on metastatic breast cancer in a mouse model. (2018) Oncol.Lett. 15:6831-6838Read more>>
- Long et al. Downregulation of MCT4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma. (2018) Cancer.Med. 7:4690-4700Read more>>
- Long Y et al. Downregulation of MCT 4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma.Cancer Med. 2018 Sep;7(9):4690-4700. Read more>>
- Meng H et al. ZG16 regulates PD-L1 expression and promotes local immunity in colon cancerTransl Oncol.2021 Feb;14(2):101003.Read more>>
- Cai, Baohuan. et al. IRAK1-regulated IFN- signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies. Mol Cancer. 2021 Dec;20(1):1-2Read more>>
- Young Min Chung. et al. Sensitizing tumors to anti-PD-1 therapy by promoting NK and CD8+ T cells via pharmacological activation of FOXO3. J Immunother Cancer. 2021 Dec;9(12):e002772Read more>>
- Young Min Chung. et al. FOXO3-dependent suppression of PD-L1 promotes anticancer immune responses via activation of natural killer cells. Am J Cancer Res. 2022; 12(3): 12411263Read more>>
- Yao Lei. et al. Phytochemical natural killer cells reprogram tumor microenvironment for potent immunotherapy of solid tumors. BIOMATERIALS. 2022 Jun;:121635Read more>>
- Wang Zhiren. et al. Sphingomyelin-derived nanovesicles for the delivery of the IDO1 inhibitor epacadostat enhance metastatic and post-surgical melanoma immunotherapy. NAT COMMUN. 2023 Nov;14(1):1-18Read more>>
- Chen Hsien-Chung. et al. Progesterone boosts abiraterone-driven target and NK cell therapies against glioblastoma. J EXP CLIN CANC RES. 2024 Dec;43(1):1-17Read more>>
Mouse Thymus cells probed with NKG2D Polyclonal Antibody, unconjugated (bs-0938R) at 1:100 dilution for 30 minutes compared to control cells (blue) and isotype control (orange)
SW480 cells were incubated in 5% BSA blocking buffer for 30 min at room temperature. Cells were then stained with NKG2D Antibody(bs-0938R)at 1:50 dilution in blocking buffer and incubated for 30 min at room temperature, washed twice with 2%BSA in PBS, followed by secondary antibody incubation for 40 min at room temperature. Acquisitions of 20,000 events were performed. Cells stained with primary antibody (green), and isotype control (orange).