bs-0931R-Biotin

DATASHEET

Host: Rabbit

Target Protein: Acetyl-Histone H1 Lys52

Specificity: This antibody will react with members of the Histone H1 family that have an acetylated lysine positioned in the motif AS(Ac-K)ER. This include H1.1, H1.2, H1.3, H1.4, and H1.5.

Modification Site: Lys52

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3008

Swiss Prot: P10412

Source: KLH conjugated synthetic acetylpeptide derived from human Histone H1.4 around acetylation site of Lys52

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 24

Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.