DATASHEET
Host:
Rabbit
Target Protein:
S-100/S100A1
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
6271
Source:
KLH conjugated synthetic peptide derived from human S100A1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
S-100 is group of solubilities, the relatively low molecular mass, the high acidic protein, is the neuroglia cell specificity protein, may also exist in the nerve fiber. In the research intestines nervous system's shape characteristic and the structural feature, S-100 has the good expressive function. The S-100 protein its physiological action was not still clear, possible and in the cell the calcium ion medium's control action concerns. The S-100 protein may exist in the neurinoma, becomes the cartilage cytoma, the chondrosarcoma, the osteosarcoma, the neuroglia lump, Lang Gehan the Si cytoma, some cancers and the melanocyte cell tumor and so on. In the immunity group, damages except the malignant melanoma skin, the S-100 protein also increases in the benign melanocyte cell mole, for example: The blue nevus, the ordinary day after tomorrow mole, the freckle type mole, the Spitz mole, the gas globuli cell mole, the pigment spindle-shaped cell mole and in the maldevelopment mole will express. Also has reported that the S-100 protein's dyeing intensity and tumour cell's melanocyte content assumes the inverse correlation. The knot contracts the organization proliferative or kisses the nerve the melanoma undyeable color. SUBUNIT: Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain.
PRODUCT SPECIFIC PUBLICATIONS
- Cheng, Lei, et al. "Lentiviral-mediated transfer of CDNF promotes nerve regeneration and functional recovery after sciatic nerve injury in adult rats."Biochemical and Biophysical Research Communications?(2013).Read more>>
- Lan Liu. et al. LCZ696 Ameliorates Tachycardia-Induced Cardiac Calcium Dyshomeostasis in the SERCA2-Dependent Pathway. TOHOKU J EXP MED. 2023 Aug 23Read more>>
- Wenjie Yue. et al. Alleviated diabetic osteoporosis and peripheral neuropathic pain by Rehmannia glutinosa Libosch polysaccharide via increasing regulatory T cells. INT J BIOL MACROMOL. 2024 Jul;:134241Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti S-100/S100A1 Polyclonal Antibody, Unconjugated (bs-0850R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Formalin-fixed and paraffin embedded mouse colon tissue labeled with Anti S-100/S100A1 Polyclonal Antibody, Unconjugated (bs-0850R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.