DATASHEET
Host:
Rabbit
Target Protein:
Lpin1 protein
Immunogen Range:
201-300/924
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
14245
Swiss Prot:
Q91ZP3
Source:
KLH conjugated synthetic peptide derived from mouse Lpin1 protein
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis. Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. Isoform 1 is recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol.
PRODUCT SPECIFIC PUBLICATIONS
- Zhiyun Hao. et al. MicroRNA-432 inhibits milk fat synthesis by targeting SCD and LPL in ovine mammary epithelial cells. Food Funct. 2021 AugRead more>>
- Mengni Bao. et al. PICALM Regulating the Generation of Amyloid -Peptide to Promote Anthracycline-Induced Cardiotoxicity. ADV SCI. 2024 Jun;:2401945Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat colon labeled with Anti Lpin1 Polyclonal Antibody, Unconjugated (bs-0759R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Formalin-fixed and paraffin embedded mouse colon labeled with Anti Lpin1 Polyclonal Antibody, Unconjugated (bs-0759R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.