DATASHEET
Host:
Rabbit
Target Protein:
PEDF
Immunogen Range:
201-300/418
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
20317
Swiss Prot:
P97298
Source:
KLH conjugated synthetic peptide derived from mouse PEDF
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
PRODUCT SPECIFIC PUBLICATIONS
- Miao et al. Vascular Endothelial Growth Factor, Basic Fibroblast Growth Factor, and Pigment Epithelium-Derived Factor Expression in the Neovascular Iris in Retinal Diseases. (2018) J.Ophthalmol. 2018:8025951Read more>>
- Yao Q et al.Lycium Barbarum Polysaccharides Improve Retinopathy in Diabetic Sprague-Dawley Rats.(2018)Evid Based Complement Alternat Med.Nov 15;2018:7943212. Read more>>
- Noy Bagdadi. et al. The Expression Levels and Cellular Localization of Pigment Epithelium Derived Factor (PEDF) in Mouse Testis: Its Possible Involvement in the Differentiation of Spermatogonial Cells. Int J Mol Sci. 2021 Jan;22(3):1147Read more>>
- Liu Zao-Ling. et al. WGCNA reveals a biomarker for cancer-associated fibroblasts to predict prognosis in cervical cancer. J CHIN MED ASSOC. 2024 Jul;:10.1097/JCMA.0000000000001129Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat brain tissue labeled Anti-PEGF Polyclonal Antibody, Unconjugated (bs-0731R) at 1:200, followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin embedded rat eye, ciliary body labeled Anti-PEGF Polyclonal Antibody, Unconjugated (bs-0731R) at 1:200, followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated(bs-0295G-Cy3)used at 1:200 dilution for 40 minutes at 37°C.