bs-0684R-PE [Conjugated Primary Antibody]
CD147 Polyclonal Antibody, PE Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD147

Immunogen Range: 301-385/385


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 682

Swiss Prot: P35613

Source: KLH conjugated synthetic peptide derived from human CD147/TCSF

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Conjugation: PE

Excitation/ Emission: 496,564nm/578nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)

Predicted Molecular Weight: 40


Cross Reactive Species: Human
Mouse
Rat
Rabbit

Predicted Cross Reactive Species: Dog
Cow
Pig
Chicken
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Tsai, Wen-Chiuan, et al. "EMMPRIN expression positively correlates with WHO grades of astrocytomas and meningiomas." Journal of Neuro-Oncology (2013): 1-10.Read more>>
  • Cui, K., et al. "Transplantation of Autologous Bone Marrow Mononuclear Cells Regulates Inflammation in a Rabbit Model of Carotid Artery Atherosclerosis." Journal of Vascular Research 53.3-4 (2016): 196-205.Read more>>
  • Xiaole Tong et al. LPS-induced inflammation disorders bone modeling and remodeling by inhibiting angiogenesis and disordering osteogenesis in chickens. Inflamm Res. 2020 Aug;69(8):765-777.Read more>>
  • Muhammad Fakhar-e-Alam Kulyar. et al. Cluster of differentiation 147 (CD147) expression is linked with thiram induced chondrocytes apoptosis via Bcl-2/Bax/Caspase-3 signalling in tibial growth plate under chlorogenic acid repercussion. Ecotox Environ Safe. 2021 Apr;213:112059Read more>>
VALIDATION IMAGES