bs-0670R-Cy3 [Conjugated Primary Antibody]
c-Jun Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: c-Jun

Immunogen Range: 31-331/331


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3725

Swiss Prot: P05412

Source: KLH conjugated synthetic peptide derived from human c-Jun

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 43


Cross Reactive Species: Human
Mouse
Rat
Chicken

Predicted Cross Reactive Species: Dog
Cow
Sheep
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang, Jihong, et al. "Interleukin 18 augments growth ability via NF-κB and p38/ATF2 pathways by targeting cylin B1, cyclin B2, cylin A2, and Bcl-2 in BRL-3A rat liver cells." Gene (2015).Read more>>
  • Zhou, Zhiwei, et al. "microRNA let-7c is essential for the anisomycin-elicited apoptosis in Jurkat T cells by linking JNK1/2 to AP-1/STAT1/STAT3 signaling." Scientific Reports 6 (2016): 24434.Read more>>
  • Zhang, Ying, et al. "Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway." Oncology Reports.Read more>>
  • Liu, Lina, et al. "Therapeutic effects of 1, 25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model." Experimental and Therapeutic Medicine 11.6 (2016): 2284-2292.Read more>>
  • Du, Jinghua, et al. "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." Molecular medicine reports 13.3 (2016): 2159-2166.Read more>>
  • Liu et al. Therapeutic effects of 1,25-dihydroxyvitamin D3 on diabetes-induced liver complications in a rat model. (2016) Exp.Ther.Me. 11:2284-2292Read more>>
  • Manabe A et al.Upregulation of transient receptor potential melastatin 6 channel expression by rosiglitazone and all-trans-retinoic acid in erlotinib-treated renal tubular epithelial cells.(2018)J Cell Physiol. Read more>>
  • Zhu G et al. TRAF6 promotes the progression and growth of colorectal cancer through nuclear shuttle regulation NF-kB/c-jun signaling pathway. Life Sci. 2019 Sep 2;235:116831.Read more>>
  • Wu Z et al. Co-infection of Mycoplasma gallisepticum and Escherichia coli Triggers Inflammatory Injury Involving the IL-17 Signaling Pathway. Front Microbiol. 2019 Nov 15;10:2615.Read more>>
  • "Zhang C et al. MiR-429 regulates rat liver regeneration and hepatocyte proliferation by targeting JUN/MYC/BCL2/CCND1 signaling pathway.Cell Signal. 2018 Oct;50:80-89."Read more>>
  • Mei Ha. et al. PKC mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism. Sci Total Environ. 2021 Feb;757:143727Read more>>
  • Guangwei Zhu. et al. The Effects of TRAF6 on Growth and Progression in Colorectal Cancer are Regulated by miRNA-140. Oncotargets Ther. 2020; 13: 11991C12001Read more>>
  • Jinhao Zeng. et al. Ginsenoside Rb1 Lessens Gastric Precancerous Lesions by Interfering With -Catenin/TCF4 Interaction. Front Pharmacol. 2021; 12: 682713Read more>>
  • Que, Tianshi. et al. HMGA1 stimulates MYH9-dependent ubiquitination of GSK-3 via PI3K/Akt/c-Jun signaling to promote malignant progression and chemoresistance in gliomas. Cell Death Dis. 2021 Dec;12(12):1-12Read more>>
  • Zhao, Lifang. et al. Real-world PM2.5 exposure induces pathological injury and DNA damage associated with miRNAs and DNA methylation alteration in rat lungs. Environ Sci Pollut R. 2022 Jan;:1-16Read more>>
  • Cuifang Chang. et al. The orphan GPR50 receptor interacting with T_RI induces G1/S-phase cell cycle arrest via Smad3-p27/p21 in BRL-3A cells. BIOCHEM PHARMACOL. 2022 Aug;202:115117Read more>>
  • Xiaobao Gong. et al. Synthesis and anti-inflammatory activity of paeonol derivatives with etherized aryl urea by regulating TLR4/MyD88 signaling pathway in RAW264.7 cell. BIOORG CHEM. 2022 Oct;127:105939Read more>>
  • Chunyan Zhang. et al. Overexpression of miR-125a-5p Inhibits Hepatocyte Proliferation through the STAT3 Regulation In Vivo and In Vitro. INT J MOL SCI. 2022 Jan;23(15):8661Read more>>
  • Jun Liu. et al. Pharmacology Mechanism of <i>Polygonum Bistorta</i> in Treating Ulcerative Colitis Based on Network Pharmacology. EVID-BASED COMPL ALT. 2022 Dec 28;2022:646156Read more>>
  • Xiaoxiang Peng. et al. Phasic regulation of the ATP/P2X7 receptor signaling pathway affects the function of antigen-presenting cells in experimental autoimmune uveitis. INT IMMUNOPHARMACOL. 2023 Jun;119:110241Read more>>
  • Hao Huang. et al. MAP4K4 is involved in the neuronal development of retinal photoreceptors. EXP EYE RES. 2023 Aug;233:109524Read more>>
  • Sun Jia. et al. ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis. BMC CANCER. 2023 Dec;23(1):1-18Read more>>
  • Guangshang Zhong. et al. Ubiquitin ligase RFWD2 promotes dendritic spine and synapse formation by activating the ERK/PEA3/c-Jun pathway in rat cerebral cortical neurons. BBA-MOL BASIS DIS. 2024 Jun;:167319Read more>>
VALIDATION IMAGES