bs-0586R [Primary Antibody]
VWF Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: VWF

Immunogen Range: 701-800/2813


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7450

Swiss Prot: P04275

Source: KLH conjugated synthetic peptide derived from human VWF

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

Size: 100ul

Concentration: 1ug/ul

Applications: IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 309


Cross Reactive Species: Human
Mouse
Rat
Rabbit

Predicted Cross Reactive Species: Dog
Cow
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Du, Fengyi, et al. "Gradient nanofibrous chitosan/poly ?-caprolactone scaffolds as extracellular microenvironments for vascular tissue engineering." Biomaterials (2011).Read more>>
  • Hsu, Chih‐Hsin, et al. "Hemodynamic, biological, and right ventricular functional changes following intraatrial shunt repair in patients with flow‐induced pulmonary hypertension." Congenital Heart Disease 12.4 (2017): 533-539.Read more>>
  • Li, Q., et al. "Development of Prevascularized Cell Sheets Using Single Bone Marrow Mesenchymal Stem Cell Source for Tissue Regeneration." J Stem Cell Res Ther 6.351 (2016): 2.Read more>>
  • Tort S et al. The effect of a new wound dressing on wound healing: Biochemical and histopathological evaluation. Burns. 2019 Dec 17. pii: S0305-4179(18)30976-8.Read more>>
  • Yao Z et al. Bone marrow mesenchymal stem cell-derived endothelial cells increase capillary density and accelerate angiogenesis in Mousehindlimb ischemia model. Stem Cell Res Ther. 2020 Jun 8;11(1):221.Read more>>
  • Xue Wang. et al. Engineered liposomes targeting the gutCCNS Axis for comprehensive therapy of spinal cord injury. J Control Release. 2021 Mar;331:39Read more>>
  • Ercan Ak?it. et al. Drug-eluting Vein Graft with Acetylsalicylic Acid-Ticagrelor-Unfractionated Heparin Complex Inhibits Early Graft Thrombosis. Balk Med J. 2020 Sep; 37(5): 269C275Read more>>
  • He, Lingnan. et al. LRG1 mediated by ATF3 promotes growth and angiogenesis of gastric cancer by regulating the SRC/STAT3/VEGFA pathway. Gastric Cancer. 2022 Jan;:1-15Read more>>
  • Jingjing Zhao. et al. Bone Regeneration and Angiogenesis by Co-transplantation of Angiotensin IIPretreated Mesenchymal Stem Cells and Endothelial Cells in Early Steroid-Induced Osteonecrosis of the Femoral Head:. Cell Transplant. 2022;()Read more>>
  • Yonghong Fan. et al. Construction of tissue-engineered vascular grafts with high patency by mimicking immune stealth and blocking TGF- mediated endothelial-to-mesenchymal transition. COMPOS PART B-ENG. 2023 Feb;251:110487Read more>>
  • Yan, Fanchen. et al. Glycoside combinations of Buyang Huanwu decoction ameliorate atherosclerosis via STAT3, HIF-1, and VEGF. N-S ARCH PHARMACOL. 2023 Jan;:1-17Read more>>
  • Tsai-Sheng Fu. et al. Biomimetic vascularized adipose-derived mesenchymal stem cells bone-periosteum graft enhances angiogenesis and osteogenesis in a male rabbit spine fusion model. BONE JOINT RES. 2023 Dec; 12(12): 722C733Read more>>
  • Tzu-Hsiang Lin. et al. A bioactive composite scaffold enhances osteochondral repair by using thermosensitive chitosan hydrogel and endothelial lineage cell-derived chondrogenic cell. MATER TODAY BIO. 2024 Oct;28:101174Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat brain tissue (bs-0586R) at 1:300 followed by conjugation to the secondary antibody and DAB staining.