bs-0567R-Cy7 [Conjugated Primary Antibody]
ITGA5 Polyclonal Antibody, Cy7 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: ITGA5

Immunogen Range: 1021-1099/1099


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3678

Swiss Prot: P08648

Source: KLH conjugated synthetic peptide derived from human ITGA5

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 110


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Cui, Li, et al. "The Role of Integrin-α5 in the Proliferation and Odontogenic Differentiation of Human Dental Pulp Stem Cells." Journal of endodontics 40.2 (2014): 235-240.Read more>>
  • Zhang, Rui, et al. "Rho/MRTF-A-Induced Integrin Expression Regulates Angiogenesis in Differentiated Multipotent Mesenchymal Stem Cells." Stem Cells International 2015 (2015).Read more>>
  • Torkamani, N., et al. "Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle." Stem Cells International 2016 (2016).Read more>>
  • Tao Wang. et al. Preliminary study on SPECT/CT imaging of pancreatic cancer xenografts by targeting integrin 5 in pancreatic stellate cells. J Cancer. 2021; 12(6): 1729C1733Read more>>
  • Song Danyang. et al. Silencing of ER-resident oxidoreductase PDIA3 inhibits malignant biological behaviors of multidrug-resistant gastric cancer. Acta Bioch Bioph Sin. 2021 AugRead more>>
  • Cui, Xiyao. et al. TMT-based proteomic analysis reveals integrins involved in the synergistic infection of reticuloendotheliosis virus and avian leukosis virus subgroup J. BMC VET RES. Bmc Vet Res. 2022 Dec;18(1):1-8Read more>>
  • Lu, Kang. et al. N-Acetyl-L-cysteine facilitates tendon repair and promotes the tenogenic differentiation of tendon stem/progenitor cells by enhancing the integrin 5/1/PI3K/AKT signaling. BMC MOL CELL BIOL. 2023 Dec;24(1):1-13Read more>>
VALIDATION IMAGES