bs-0421R-Cy3 [Conjugated Primary Antibody]
DR3 Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: DR3

Immunogen Range: 351-417/417


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8718

Swiss Prot: Q93038

Source: KLH conjugated synthetic peptide derived from human DR3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 43


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ślebioda, Tomasz Jerzy, et al. "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients."Scandinavian Journal of Immunology (2015).Read more>>
  • Sen Li. et al. Quinic acid alleviates high-fat diet-induced neuroinflammation by inhibiting DR3/IKK/NF-B signaling via gut microbial tryptophan metabolites. GUT MICROBES. 2024 07Read more>>
VALIDATION IMAGES