bs-0351R-BF594 [Conjugated Primary Antibody]
GLUT2 Polyclonal Antibody, AbBy Fluor® 594 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: GLUT2

Immunogen Range: 431-524/524


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6514

Swiss Prot: P11168

Source: KLH conjugated synthetic peptide derived from human GLUT2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.

Conjugation: AbBy Fluor® 594

Excitation/ Emission: 590nm/617nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 54


Cross Reactive Species: Human
Mouse
Rat
Goat
Others

Predicted Cross Reactive Species: Dog
Cow
Sheep
Pig
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Guttman, Ofer, et al. "α1‐Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet β‐cells in favor of protection from autoimmune diabetes." Immunology (2014).Read more>>
  • Zheng, Liming, et al. "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." Scientific Reports 6 (2016): 37414.Read more>>
  • Guttman et al. α1-Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet β-cells in favor of protection from autoimmune diabetes. (2014) Immunology. Read more>>
  • Wang,et al.Oat globulin peptides regulate antidiabetic drug targets and glucose transporters in Caco-2 cells.(2018) Journal of Functional Foods. 42:12-20.Read more>>
  • Wang N et al. Fibroblast growth factor 21 improves glucose homeostasis partially via down-regulation of Na+-d-glucose cotransporter SGLT1 in the small intestine.(2019) Biomedicine & Pharmacotherapy, 109, 1070–1077. Read more>>
  • Jiang T et al. Protein-bound Anthocyanin Compounds of Purple Sweet Potato (p-BAC-PSP) Ameliorate Hyperglycemia by Regulating Hepatic Glucose Metabolism in High Fat Diet/Streptozotocin-Induced Diabetic Mice. J Agric Food Chem. 2020 Feb 12;68(6):1596-1608.Read more>>
  • "Tian C et al. Short communication: A high-grain diet entails alteration in nutrient chemosensing of the rumen epithelium in goats. Animal Feed Science and Technology. Volume 262, April 2020, 114410. "Read more>>
  • Pengli Wang. et al. The AT1 receptor autoantibody causes hypoglycemia in fetal rats via promoting the STT3A-GLUT1-glucose uptake axis in liver. Mol Cell Endocrinol. 2020 Dec;518:111022Read more>>
  • Wang Zhe. et al. Total flavonoids of Astragalus Ameliorated Bile Acid Metabolism Dysfunction in Diabetes Mellitus. Evid-Based Compl Alt. 2021;2021:6675567Read more>>
  • Yu-Zhong Chen. et al. Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice. FRONT NUTR. 2022; 9: 854725Read more>>
  • Lihuan Zhang. et al. Effects of three probiotics and their interactions on the growth performance of and nutrient absorption in broilers. PEERJ. 2022 May;10:e13308Read more>>
  • Johan K. E. Spetz. et al. Heightened apoptotic priming of vascular cells across tissues and life span predisposes them to cancer therapyCinduced toxicities. SCI ADV. 2022 NovRead more>>
  • Yang Liu. et al. Methylation, Hydroxylation, Glycosylation and Acylation Affect the Transport of Wine Anthocyanins in Caco-2 Cells. FOODS. 2022 Jan;11(23):3793Read more>>
  • Qun Cheng. et al. Zearalenone Exposure Affects the Keap1–Nrf2 Signaling Patway and Glucose Nutrient Absorption Related Genes of Porcine Jejunal Epithelial Cells. TOXINS. 2022 Nov;14(11):793Read more>>
  • Huiqin Guo. et al. Oat -D-glucan ameliorates type II diabetes through TLR4/PI3K/AKT mediated metabolic axis. INT J BIOL MACROMOL. 2023 Jul;:126039Read more>>
  • Tianfeng Chen. et al. Islet hypoplasia of adult offspring rats caused by intrauterine chronic hypoxia is compensated by up-regulation of INS and PDX-1. ISLETS. 2023;15(1):Article: 223161Read more>>
  • Yadi Liu. et al. Rutin ameliorated lipid metabolism dysfunction of diabetic NAFLD via AMPK/SREBP1 pathway. PHYTOMEDICINE. 2024 Apr;126:155437Read more>>
  • Jing Zhao. et al. Differentiation of intestinal stem cells toward goblet cells under systemic iron overload stress are associated with inhibition of Notch signaling pathway and ferroptosis. REDOX BIOL. 2024 Jun;72:10316Read more>>
  • Cheng Aoming. et al. The enhanced energy metabolism in the tumor margin mediated by RRAD promotes the progression of oral squamous cell carcinoma. CELL DEATH DIS. 2024 May;15(5):1-14Read more>>
VALIDATION IMAGES