bs-0293R
[Secondary Antibody]
Rabbit Anti-Rat IgG Antibody (H+L)
DATASHEET
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Purification: Purified by Protein A.
Storage Buffer: Lyophilized
Storage: Store at -20°C for 12 months.
Background:
Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
Size: 1mg
Concentration: Determined by end user
Applications:
WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Cross Reactive Species: Rat
For research use only. Not intended for diagnostic or therapeutic use.
PRODUCT SPECIFIC PUBLICATIONS
- Xu, Hua, et al. "Low and High Doses of Ursolic Acid Ameliorate Experimental Autoimmune Myasthenia Gravis through Different Pathways." Journal of Neuroimmunology (2015).Read more>>
- Wang et al. Caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate dendric cell IL-1-IL-17 pathway. (2015) J.Neuroinflammatio. 12:118Read more>>
- Wang et al. Caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate dendric cell IL-1-IL-17 pathway. (2015) J.Neuroinflammatio. 12:118Read more>>
- Liang et al. Protection Effect of Zhen-Wu-Tang on Adriamycin-Induced Nephrotic Syndrome via Inhibiting Oxidative Lesions and Inflammation Damage. (2014) Evid.Based.Complement.Alternat.Med. 2014:131604Read more>>
- Li et al. Exosomes derived from atorvastatin-modified bone marrow dendritic cells ameliorate experimental autoimmune myasthenia gravis by up-regulated levels of IDO/Treg and partly dependent on FasL/Fas pathway. (2016) J.Neuroinflammation. 13:8Read more>>
- Saarinen,et al.A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.(2018) Scientific Reports. 8:33.Read more>>
- Fan,et al.Antitumor activity and underlying mechanism of Sargassum fusiforme polysaccharides in CNE-bearing mice.(2018) International Journal of Biological Macromolecules. 112:516-522.Read more>>
- Li et al. Nobiletin protects PC12 cells from ERS-induced apoptosis in OGD/R injury via activation of the PI3K/AKT pathway. (2018) Exp.Ther.Med. 16:1470-1476Read more>>
- Hong Y et al. The neuroprotection of progesterone against Aβ-induced NLRP3-Caspase-1 inflammasome activation via enhancing autophagy in astrocytes. Int Immunopharmacol. 2019 Jun 5;74:105669. Read more>>
- Li Z et al. Expression and localization analyses of the cholinergic anti-inflammatory pathway and α7nAchR in different tissues of rats with rheumatoid arthritis. Acta Histochem. 2019 Aug;121(6):742-749.Read more>>
- Zhang Y et al. Angiotensin Ⅱ deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through AT1R/ROS/p38MAPK/ADAM17 pathway. Am J Physiol Cell Physiol. 2019 Aug 7.Read more>>
- Li ZR et al. Nobiletin protects PC12 cells from ERS‑induced apoptosis in OGD/R injury via activation of the PI3K/AKT pathway.Exp Ther Med. 2018 Aug;16(2):1470-1476.Read more>>
- Honglian Liet al. Zhen-Wu-Tang Protects IgA Nephropathy in Rats by Regulating Exosomes to Inhibit NF-B/NLRP3 Pathway. Front Pharmacol. 2020 Jul 16;11:1080.Read more>>
- Xinheng Zhanget al. gga?microRNA?375 negatively regulates the cell cycle and proliferation by targeting Yes?associated protein 1 in DF?1 cells. Exp Ther Med. 2020 Jul;20(1):530-542.Read more>>
- Yun-Peng Li. et al. Piperine protects against myocardial ischemia/reperfusion injury by activating the PI3K/AKT signaling pathway. Exp Ther Med. 2021 Apr;21(4):1-8Read more>>
- Meng Kong. et al. Expression of the axon guidance factor Slit2 and its receptor Robo1 in patients with Hirschsprung disease: An observational study. Medicine. 2021 Aug 20; 100(33): e26981Read more>>
- Ryo Mitsui. et al. Efficient cell transplantation combining injectable hydrogels with control release of growth factors. Regen Ther. 2021 Dec;18:372Read more>>
- Xiao, Yan. et al. Rise in Postprandial GLP-1 Levels After Roux-en-Y Gastric Bypass: Involvement of the Vagus NerveSpleen Anti-inflammatory Axis in Type 2 Diabetic Rats. Obes Surg. 2022 Jan;:1-9Read more>>
- Yin Wuzhong. et al. Oryza sativa PECTIN DEFECTIVE TAPETUM1 affects anther development through a pectin-mediated signaling pathway in rice. PLANT PHYSIOL. 2022 ApRead more>>
- Zhihai Yu. et al. Two contradictory facades of N-acetylcysteine activity towards renal carcinoma cells. J TAIBAH UNIV SCI. 2022;16(1):423-431Read more>>
- Zhongxiao Zhou. et al. Formononetin regulates endothelial nitric oxide synthase to protect vascular endothelium in deep vein thrombosis rats:. INT J IMMUNOPATH PH. 2022;()Read more>>
- Fang Shi. et al. Phosphatidylinositol 3-Kinase/Protein Kinase B/Mammalian Target of the Rapamycin Pathway-Related Protein Expression in Lung Squamous Cell Carcinoma and Its Correlation with Lymph Node Metastasis.. J ONCOL. 2022 Aug;2022:4537256-4537256Read more>>
- Yaru Lu. et al. JAK2 inhibitor ameliorates the progression of experimental autoimmune myasthenia gravis and balances Th17/Treg cells via regulating the JAK2/STAT3-AKT/mTOR signaling pathway. INT IMMUNOPHARMACOL. 2023 Feb;115:109693Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Rat IgG Polyclonal Antibody, Unconjugated (bs-0293R) at 1:600, followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Rat IgG Polyclonal Antibody, FITC conjugated (bs-0293R-FITC) at 1:200, followed by DAPI staining
Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Rat IgG Polyclonal Antibody, FITC conjugated (bs-0293R-FITC) at 1:200