DATASHEET
Host:
Rabbit
Target Protein:
VPAC2R
Immunogen Range:
81-170/437
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
29555
Swiss Prot:
P35000
Source:
KLH conjugated synthetic peptide derived from rat VIP receptor II
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
PRODUCT SPECIFIC PUBLICATIONS
- Ruan, Ming, et al. "Attenuation of stress-induced gastrointestinal motility disorder by gentiopicroside, from Gentiana macrophylla Pall." Fitoterapia(2015).Read more>>
- Ye D et al. Spatiotemporal Expression Changes of PACAP and Its Receptors in Retinal Ganglion Cells After Optic Nerve Crush.(2018)J Mol Neurosci. Nov 10.Read more>>
- Zeqi Tang. et al. Seasonal changes in the expression of PACAP, VPAC1, VPAC2, PAC1 and testicular activity in the testis of the muskrat (Ondatra zibethicus). EUR J HISTOCHEM. 2022 Mar 24; 66(2): 3398Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti VIP receptor 2/VPAC2 Polyclonal Antibody, Unconjugated (bs-0197R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
A431 lysates probed with VPAC2R Polyclonal Antibody, Unconjugated (bs-0197R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.
Lane 1: Recombinant human VIPR2 protein, N-Trx-His(bs-42334P) probed with VIPR2 Polyclonal Antibody, Unconjugated (bs-0197R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.