DATASHEET
Host:
Rabbit
Target Protein:
PACAP-27/38
Immunogen Range:
132-169/176
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
116
Swiss Prot:
P18509
Source:
KLH conjugated synthetic peptide derived from human PACAP-27/38
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.
PRODUCT SPECIFIC PUBLICATIONS
- Lu L et al. Beneficial Effects of Crocin against Depression via Pituitary Adenylate Cyclase-Activating Polypeptide. Biomed Res Int. 2020 Jun 24;2020:3903125.Read more>>
- Hailou Zhang. et al. Synergistic effects of two natural compounds of iridoids on rapid antidepressant action by up-regulating hippocampal PACAP signaling. 2022 Mar 31Read more>>
- Zeqi Tang. et al. Seasonal changes in the expression of PACAP, VPAC1, VPAC2, PAC1 and testicular activity in the testis of the muskrat (Ondatra zibethicus). EUR J HISTOCHEM. 2022 Mar 24; 66(2): 3398Read more>>
- Han Xuke. et al. Effects of electroacupuncture on bladder dysfunction and the expression of PACAP38 in a diabetic rat model. FRONT PHYSIOL. 2022 Dec;13:2751Read more>>
- Alice Meng. et al. mGluR5 in astrocytes in the ventromedial hypothalamus regulates PACAP neurons and glucose homeostasis. J NEUROSCI. 2023 JulRead more>>
VALIDATION IMAGES
Rat cerebrum lysates probed with PACAP-27/38 Polyclonal Antibody, Unconjugated (bs-0190R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Rat cerebrum lysates probed with PACAP-27/38 Polyclonal Antibody, Unconjugated (bs-0190R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.