DATASHEET
Host:
Rabbit
Target Protein:
Neurokinin B receptor
Immunogen Range:
151-250/440
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
6870
Swiss Prot:
P29371
Source:
KLH conjugated synthetic peptide derived from human NKR
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
PRODUCT SPECIFIC PUBLICATIONS
- OBATA, KYOICHI, et al. "Tachykinin Receptor 3 Distribution in Human Oral Squamous Cell Carcinoma." Anticancer Research 36.12 (2016): 6335-6341.Read more>>
- OBATA, KYOICHI, et al. "Role of Neurokinin 3 Receptor Signaling in Oral Squamous Cell Carcinoma." Anticancer Research 37.11 (2017): 6119-6123.Read more>>
- Shoko Yoshida. et al. Expression of Neurokinin B Receptor in the Gingival Squamous Cell Carcinoma Bone Microenvironment. Diagnostics. 2021 Jun;11(6):1044Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat uterine myoma labeled with Rabbit Anti-ER-beta Polyclonal Antibody (bs-0166R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Formalin-fixed and paraffin embedded rat uterine myoma labeled with Rabbit Anti-ER-beta Polyclonal Antibody (bs-0166R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
RSC96 cells probed with Neurokinin B receptor Antibody, unconjugated (bs-0166R) at 1:100 dilution for 30 minutes compared to control cells (blue) and isotype control (orange)