DATASHEET
Host:
Rabbit
Target Protein:
GAP43
Immunogen Range:
9-100/238
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
14432
Swiss Prot:
P06837
Source:
KLH conjugated synthetic peptide derived from mouse GAP43
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
PRODUCT SPECIFIC PUBLICATIONS
- Jiang et al. Effect of Frankincense Extract on Nerve Recovery in the Rat Sciatic Nerve Damage Model. (2016) Evid.Based.Complement.Alternat.Med. 2016:3617216Read more>>
- Zhai X et al. L-lactate preconditioning promotes plasticity-related proteins expression and reduces neurological deficits by potentiating GPR81 signaling in rat traumatic brain injury model. Brain Res. 2020 Nov 1;1746:146945.Read more>>
- Sheng Cao. et al. Ultrasound-targeted microbubble destruction-mediated Ang1 gene transfection improves left ventricular structural and sympathetic nerve remodeling in canines with myocardial infarction. Ann Transl Med. 2021 Feb; 9(3): 221Read more>>
- Han Yang. et al. A Novel Targeted and High\Efficiency Nanosystem for Combinational Therapy for Alzheimer's Disease. Adv Sci. 2020 Oct;7(19):1902906Read more>>
- Yifan Wang. et al. Positive effect of Astragaloside IV on neurite outgrowth via talin\dependent integrin signaling and microfilament force. J Cell Physiol. 2021 Mar;236(3):2156-2168Read more>>
- Pingan Chen. et al. The influence of inhibiting renal neural regeneration on the efficacy of renal denervation to chronic heart failure. 2021 Oct 22Read more>>
- Erdal Ayhan I_ik. et al. Use of Erythropoietin and Fibrin Glue Mixture for Peripheral Nerve Repair. Plast Reconstr Surg. 2022 Feb;149(2):395-403Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-GAP-43 Polyclonal Antibody, Unconjugated (bs-0154R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-GAP-43 Polyclonal Antibody, Unconjugated (bs-0154R) at 1:300 followed by conjugation to the secondary antibody and DAB staining
HeLa cells probed with GAP43 Polyclonal Antibody, unconjugated (bs-0154R) at 1:100 dilution for 30 minutes compared to control cells (blue) and isotype control (orange)