bs-0124R-Cy3 [Conjugated Primary Antibody]
Calcitonin receptor Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Calcitonin receptor

Immunogen Range: 31-120/516


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 116506

Swiss Prot: P32214

Source: KLH conjugated synthetic peptide derived from rat Calcitonin receptor

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 53


Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Su, Jiansheng, et al. "Ibuprofen Rescues Abnormalities in Periodontal Tissues in Conditional Presenilin 1 and Presenilin 2 Double Knockout Mice."International Journal of Molecular Sciences?14.9 (2013): 18457-18469.Read more>>
  • Tsukamoto, Manabu, et al. "Elcatonin prevents bone loss caused by skeletal unloading by inhibiting preosteoclast fusion through the unloading-induced high expression of calcitonin receptors in bone marrow cells." Bone (2016).Read more>>
  • Zhou, Zhen, et al. "The effects of ZJXG decoction on the serum CT levels and the expressions of CTR and Cbfα1 in callus of femur fracture rats." Biomedical Research 27.3 (2016): 762-768.Read more>>
  • Han, Wenfei. et al. "Abnormalities in periodontal and salivary tissues in conditional presenilin 1 and presenilin 2 double knockout mice." Molecular and Cellular Biochemistry. 347 (2011):13-30Read more>>
  • Bobek J et al. Onset of calciotropic receptors during the initiation of mandibular/alveolar bone formation. Ann Anat. 2019 Oct 12;227:151427.Read more>>
  • Yanmei He. et al. A combinational chemo-immune therapy using an enzyme-sensitive nanoplatform for dual-drug delivery to specific sites by cascade targeting. Sci Adv. 2021 Feb;7(6):eaba0776Read more>>
  • Tian Zhang. et al. Supramolecular Tadalafil Nanovaccine for Cancer Immunotherapy by Alleviating Myeloid-Derived Suppressor Cells and Heightening Immunogenicity. 2021 May 13Read more>>
  • Jessika Appelt. et al. Mice Lacking the Calcitonin Receptor Do Not Display Improved Bone Healing. Cells-Basel. 2021 Sep;10(9):2304Read more>>
  • Zhen-Han Feng. et al. A combination strategy based on an Au nanorod/doxorubicin gel via mild photothermal therapy combined with antigen-capturing liposomes and anti-PD-L1 agent promote a positive shift in the cancer-immunity cycle. Acta Biomater. 2021 OcRead more>>
  • Tazio Maleitzke. et al. The calcitonin receptor protects against bone loss and excessive inflammation in collagen antibody-induced arthritis. Iscience. 2022 Jan;25:103689Read more>>
  • Tong Gao. et al. Macrophage-camouflaged epigenetic nanoinducers enhance chemoimmunotherapy in triple negative breast cancer. ACTA PHARM SIN B. 2022 NovRead more>>
  • Wenhuan Chai. et al. Visualizing Cathepsin K-Cre Expression at the Single-Cell Level with GFP Reporters. JBMR Plus. 2022 Dec;:e10706Read more>>
  • Linlin Tao. et al. Synergistic strategy based on mild phototherapy and deep tumor hypoxia reversal comprehensively remodels the tumor microenvironment for improved immunotherapy. CHEM ENG J. 2023 Sep;472:145092Read more>>