bs-0111R-BF750 [Conjugated Primary Antibody]
Progesterone Receptor Antibody, AbBy Fluor® 750 Conjugated
www.biossusa.com
[email protected]
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+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Progesterone Receptor

Immunogen Range: 501-600/933


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5241

Swiss Prot: P06401

Source: KLH conjugated synthetic peptide derived from human progesterone receptor

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.

Conjugation: AbBy Fluor® 750

Excitation/ Emission: 749nm/775nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 103


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Chu, Meiqiang, et al. "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." Molecular and Cellular Endocrinology (2017).Read more>>
  • Xiangguo Wang. et al. Exosomes from bovine endometrial epithelial cells ensure trophoblast cell development by miR\218 targeting secreted frizzled related protein 2. 2020 Nov 23Read more>>
  • Ruddenklau Amy. et al. Validation of a new Custom Polyclonal Progesterone Receptor Antibody for Immunohistochemistry in the Female Mouse Brain. Journal of the Endocrine Society. 2023 Aug;7(10)Read more>>
VALIDATION IMAGES