bs-0054R [Primary Antibody]
GDNF Receptor alpha 2 Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: GDNF Receptor alpha 2

Immunogen Range: 301-360/464


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2675

Swiss Prot: O00451

Source: KLH conjugated synthetic peptide derived from human GDNF Receptor alpha 2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 47


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ye F et al. Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos-and FosB-dependent IL-8 induction in injured mouse epidermis. Toxicol Lett. 2019 Oct 19. pii: S0378-4274(19)30325-X.Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat brain labeled with Anti-GDNF-Receptor-alpha-2 Polyclonal Antibody, Unconjugated(bs-0054R) 1:200 followed by conjugation to the secondary antibody and DAB staining


Lane 1: Hela cell lysates probed with GDNF Receptor alpha 2 Polyclonal Antibody, Unconjugated (bs-0054R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.


Lane 1: Mouse Cerebrum tissue lysates; Lane 2: Mouse Liver tissue lysates probed with GDNF Receptor alpha 2 Polyclonal Antibody, Unconjugated (bs-0054R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.